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Fabry's disease: a multidisciplinary disorder
F P Peters1, A Sommer, A Vermeulen
1Department of Internal Medicine, University Hospital Maastricht, The Netherlands.
Postgraduate Medical Journal
|March 31, 1998
Abstract:
Fabry's disease is an X-linked hereditary disorder resulting in accumulation of a glycolipid (galactosylgalactosyl glucosylceramide) due to deficiency of alpha-galactosidase A. The diagnosis can be made by histopathologic examination of skin biopsy, low activity of alpha-galactosidase in leucocytes and genetic examination. Treatment is symptomatic. We want to stress the multidisciplinary collaboration necessary to deal with this condition, in order to prevent acceleration of symptoms.