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Management of primary corneal graft failure
P D Van Rensburg1, I M Raber, P R Laibson
1Cornea Service, Wills Eye Hospital, Philadelphia, Pennsylvania, USA.
Cornea
|March 31, 1998
Summary
Primary graft failure (PGF) after penetrating keratoplasty (PK) is rare. Observing for 3-4 weeks before repeat PK may allow spontaneous graft clearing, leading to good visual outcomes.
Area of Science:
- Ophthalmology
- Transplantation Surgery
Background:
- Primary graft failure (PGF) is an uncommon complication following penetrating keratoplasty (PK).
- Management strategies for early PGF vary, impacting long-term visual prognosis.
Observation:
- Two cases of PGF occurred in patients receiving grafts from a common donor, operated on by different surgeons.
- Both patients presented with significant early postoperative graft edema and haze.
Findings:
- Case 1 underwent repeat PK after 4 weeks with successful graft clarity and visual acuity.
- Case 2 experienced gradual graft clearing over 6 months without repeat surgery, achieving similar visual acuity.
Implications:
- Observation for 3-4 weeks is recommended before considering repeat PK for apparent PGF.
- Spontaneous graft clearing is possible, potentially avoiding further surgical intervention.
- This approach can lead to favorable visual outcomes in PGF cases.