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Related Experiment Videos

[The P-pill for men--when will it be available?]

M Ulstein1

  • 1Kvinneklinikken Haukeland Sykehus, Bergen.

Tidsskrift for Den Norske Laegeforening : Tidsskrift for Praktisk Medicin, Ny Raekke
|April 1, 1998
PubMed
Summary

Developing male hormonal contraceptives faces challenges, but prototypes show promise. Steroid regimens are effective and reversible, particularly in Asian men, though further research on androgens and funding is crucial.

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International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics·2000

Area of Science:

  • Reproductive endocrinology
  • Male contraception development
  • Pharmacology

Context:

  • Male hormonal contraception development is complex, with ongoing research into various methods.
  • Existing experimental prototypes demonstrate potential but require further refinement.
  • Steroid regimens show efficacy and reversibility, with notable ethnic variations.

Purpose:

  • To review the current status and challenges in developing hormonal contraceptives for men.
  • To highlight promising strategies like steroid regimens and gonadotropin-releasing hormone (GnRH) analogues.
  • To identify key areas for future research, including androgen supplementation and potential side effects.

Summary:

  • Several hormonal contraceptive prototypes for men are under development, with steroid regimens showing particular promise.
  • Steroid regimens are effective, reversible, and cost-efficient, with higher efficacy observed in Asian men.
  • Gonadotropin-releasing hormone (GnRH) analogues are promising but require further investigation. Androgen supplementation is essential for maintaining sexual function across all hormonal strategies.

Impact:

  • Clarifying the impact of androgens on lipid metabolism and prostate physiology is critical for safety.
  • Securing adequate funding is the primary barrier to advancing male contraceptive research and development.
  • Successful development could offer a significant new option for male family planning and reproductive health.

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