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[Arrhythmogenic right ventricular cardiomyopathy]

M Benn1, P S Hansen, B Lund

  • 1Arhus Universitetshospital, Skejby Sygehus, hjertemedicinsk afdeling B.

Ugeskrift for Laeger
|April 1, 1998
PubMed
Summary

Arrhythmogenic right ventricular dysplasia (ARVD) is a rare heart condition causing dangerous arrhythmias and sudden death in young people. This review covers ARVD

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Area of Science:

  • Cardiology
  • Genetics
  • Pathology

Context:

  • Arrhythmogenic right ventricular dysplasia (ARVD) is a significant cause of sudden cardiac death in young, healthy individuals.
  • It is characterized by fibrofatty replacement of the right ventricle, leading to ventricular arrhythmias.
  • Despite its rarity, ARVD poses a considerable risk for ventricular tachyarrhythmia and mortality.

Purpose:

  • To provide a comprehensive review of current knowledge on ARVD.
  • To highlight the importance of recognizing ARVD as a cause of syncope, ventricular tachycardia, and sudden cardiac death.
  • To consolidate information on epidemiology, diagnosis, symptoms, etiology, pathogenesis, prognosis, and treatment.

Summary:

  • This review synthesizes current understanding of arrhythmogenic right ventricular dysplasia (ARVD), a rare cardiomyopathy.

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  • It details the disease's epidemiology, diagnostic criteria, clinical manifestations, and proposed etiological and pathogenetic mechanisms.
  • Prognosis and therapeutic strategies for ARVD are also discussed, emphasizing its role in sudden cardiac death.

    • Impact:

    • Enhances clinical awareness of ARVD as a cause of syncope and sudden cardiac death in young individuals.
    • Provides a valuable resource for clinicians and researchers regarding ARVD diagnosis and management.
    • Contributes to a better understanding of the genetic and molecular basis of ARVD, potentially guiding future research.