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[Postoperative prophylaxis of thromboembolism. Present position.(author's transl)]
Insights
Thromboembolism prophylaxis includes anticoagulants and antiplatelets. While some drugs have contraindications or administration challenges, preoperative Heparin and Dextran preparations offer promising reductions in coagulation complications.
Area of Science:
- Medical Science
- Pharmacology
Background:
- Thromboembolism necessitates effective prophylactic measures.
- Current prophylactic agents include anticoagulants and antiplatelet drugs.
Abstract:
Only anti-coagulators and aggregation-stoppers may be said to be the medicamental prophylaxis of thromboembolism. The Cumarin-Indandion group is burdened with continuous laboratory controls. Contraindications excluding a general prophylaxis for this group as well as for Heparin and ASS exist. Infukoll, which is virtually always applicable, has the disadvantage that it has to be infused. Heparin- and Dextranspreparations however can already be used preoperatively, which means that a further decline of the coagulation complications can be expected.