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Successful treatment of in-transit metastases from Merkel's cell carcinoma with isolated hyperthermic limb perfusion
A S Gupta1, S Heinzman, E A Levine
1Department of Surgery, Louisiana State University and the Stanley S. Scott Cancer Center, New Orleans 70112, USA.
Southern Medical Journal
|April 1, 1998
Abstract:
Merkel's cell carcinoma is an uncommon neuroendocrine cutaneous neoplasm. An unusual mode of dissemination of this tumor is the phenomenon of in-transit metastases. We report complete resolution of in-transit metastases from a Merkel's cell carcinoma in response to treatment with isolated hyperthermic limb perfusion with melphalan. Limb perfusion appears to be a promising modality for such lesions.