Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Anaphylaxis in children: clinical and allergologic features

E Novembre1, A Cianferoni, R Bernardini

  • 1Allergy and Clinical Immunology Unit, Department of Pediatrics, Florence, Italy.

Pediatrics
|April 9, 1998
PubMed
Summary

In children, food allergies like seafood and milk are common triggers for anaphylaxis (a severe allergic reaction). Prevention is difficult, and epinephrine, the primary treatment, is often underutilized.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Food-induced anaphylaxis following skin prick testing: a case report and literature review.

Frontiers in allergy·2026
Same author

Re: Bobelyak M, Vaculik J, Stepan JJ. Bone mineral density assessment using Radiofrequency Echographic Mult Spectrometry (REMS) in patients before and after total hip replacement, Osteoporos Int 2025;https://doi.org/10.1007/s00198-025-07685-w and Re: Pocock N, Chan D. Editorial: Is REMS-BMD truly a measured parameter? A call for transparency and technical clarification, Osteoporos Int 2025;https://doi.org/10.1007/s00198-025-07699-4.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2025
Same author

Otitis Media With Effusion (OME) and Eustachian Tube Dysfunction: The Role of Allergy and Immunity-An EAACI Position Paper.

Allergy·2025
Same author

Eosinophilic esophagitis as a side-effect of allergen immunotherapy: protocol for a systematic review and meta-analysis.

European annals of allergy and clinical immunology·2023
Same author

Conversion of quinoa and lupin agro-residues into biochar in the Andes: An experimental study in a pilot-scale auger-type reactor.

Frontiers in bioengineering and biotechnology·2022
Same author

Impact of Food Matrices on Digestibility of Allergens and Poorly Allergenic Homologs.

Frontiers in allergy·2022

Area of Science:

  • Pediatric Allergy and Immunology
  • Clinical Medicine
  • Epidemiology

Background:

  • Anaphylaxis is a critical condition with limited data on its clinical presentation in children.
  • Understanding the specific features of pediatric anaphylaxis is crucial for effective management and prevention strategies.

Purpose of the Study:

  • To investigate the clinical and allergologic characteristics of anaphylaxis in pediatric patients.
  • To identify common triggers, symptoms, and demographic factors associated with anaphylaxis in children.

Main Methods:

  • Retrospective analysis of 95 anaphylaxis episodes in 76 children (1994-1996) at a pediatric allergology unit.
  • Evaluation of patient history, atopic status, skin prick test results, causative agents, clinical manifestations, and treatment interventions.

Related Experiment Videos

Main Results:

  • Foods (57%), particularly seafood and milk, were the most frequent triggers. Other causes included drugs, venom, and exercise.
  • Food-induced anaphylaxis was more common in younger children with eczema; exercise-induced anaphylaxis in older children with urticaria-angioedema.
  • Skin and respiratory symptoms appeared earlier and were more frequent than gastrointestinal or cardiovascular symptoms. Epinephrine was underused in treatment.

Conclusions:

  • Foods are primary anaphylaxis triggers in this pediatric cohort, with specific allergens and patient profiles varying by reaction type.
  • Prevention of anaphylaxis is challenging due to the infrequent occurrence of multiple episodes per child.
  • Underutilization of epinephrine, the first-line treatment, highlights a gap in anaphylaxis management protocols.