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A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
[Eruptive melanocytic nevi after chemotherapy]
S Karrer1, R M Szeimies, W Stolz
1Dermatologische Klinik und Poliklinik, Universität Regensburg.
Background:
Induction of melanocytic naevi by chemotherapy in children is reported in the literature. The reason for this phenomenon is not known yet.
History And Clinical Findings:
We present a 6-year-old girl who fell ill with acute lymphoblastic leukemia at the age of 2 years. After a combined chemotherapeutic treatment for 2 years followed by complete remission of leukemia, many (> 100) small pigmented naevi appeared over the whole body. The naevi did not show features suggestive of dysplasia.
Conclusions:
Patients with excess numbers of melanocytic naevi constitute a risk group for malignant melanoma, therefore periodic skin examination is recommended.
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