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Anterior chamber angle biometry: quadrant variation, age change and sex difference
H B Chen1, K Kashiwagi, S Yamabayashi
1Department of Ophthalmology, Yamanashi Medical University, Japan.
Current Eye Research
|April 2, 1998
Summary
Anterior change angle width (ACAW) decreases with age, particularly in the lateral quadrant. This narrowing is more pronounced in females over middle age, potentially linked to angle closure glaucoma risk.
Area of Science:
- Ophthalmology
- Anatomy
- Gerontology
Background:
- The anterior chamber angle's width is crucial for intraocular pressure regulation.
- Aging and sex are potential factors influencing anterior eye segment dimensions.
- Quantitative analysis of anterior chamber angle width (ACAW) is essential for understanding ocular health.
Purpose of the Study:
- To quantitatively measure anterior change angle width (ACAW) in healthy volunteers.
- To investigate the influence of aging on ACAW using an anterior eye segment analysis system.
- To determine the role of sex and age in ACAW variations.
Main Methods:
- Utilized the NIDEK EAS-1000 anterior eye segment analysis system for non-invasive ACAW measurement.
- Analyzed ACAW in upper, lower, medial, and lateral quadrants of 42 healthy volunteers' eyes.
- Employed age-matched cohorts to examine sex and aging effects on ACAW.
Main Results:
- No significant inter-quadrant ACAW differences were observed in young subjects.
- ACAW demonstrated a significant negative correlation with age across all quadrants.
- The lateral quadrant exhibited greater age-related narrowing; females showed more pronounced narrowing than males after middle age.
Conclusions:
- ACAW decreases with age, with notable narrowing in the lateral quadrant.
- Age-related ACAW reduction is more significant in females, especially those over middle age.
- The pronounced narrowing in older females may correlate with the higher incidence of angle closure glaucoma in this demographic.