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Odontogenic ghost cell tumor: a case report with cytologic findings
C H Stone1, A R Gaba, M S Benninger
1Department of Pathology, Henry Ford Hospital, Detroit, MI 48202, USA.
Diagnostic Cytopathology
|April 2, 1998
Summary
Fine-needle aspiration biopsy (FNAB) successfully diagnosed a rare odontogenic ghost cell tumor. Cytologic findings in the aspirate closely matched the tumor's histologic features, aiding diagnosis.
Area of Science:
- Oral Pathology
- Cytopathology
- Head and Neck Neoplasms
Background:
- Odontogenic ghost cell tumor is a rare neoplastic entity.
- Cytologic features of this tumor have not been previously reported.
- Calcifying odontogenic cyst, also known as Gorlin cyst, is a related entity.
Observation:
- A case of odontogenic ghost cell tumor was diagnosed using fine-needle aspiration biopsy (FNAB).
- The aspirate contained basaloid epithelial cells, ghost cells, multinucleated giant cells, and eosinophilic dentinoid material.
- Calcific debris was also noted in the aspirate.
Findings:
- The cytologic findings from FNAB closely mirrored the known histologic features of odontogenic ghost cell tumor.
- This case establishes the utility of FNAB in diagnosing this rare odontogenic neoplasm.
- Key diagnostic features include the presence of ghost cells and basaloid cells.
Implications:
- FNAB provides a valuable diagnostic tool for odontogenic ghost cell tumors.
- Accurate cytologic diagnosis can guide appropriate clinical management.
- Differential diagnoses include other odontogenic tumors and various carcinomas.