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[Adenosine deaminase: isoenzymes ADA1 and ADA2]
M Kopff1, A Kopff, S Puczkowski
1Zakładu Biochemii Katedry Nauk Podstawowych Wojskowej Akademii Medycznej.
Abstract:
The isoenzymes ADA1 and ADA2 of the enzyme adenosine deaminase (ADA 3.5.4.4) deaminate mainly two nucleotides: adenosine and 2'-deoxyadenosine, molecules with many effects on human cells. Thus, the ADA1 and ADA2 in human cells are of extreme importance. Biochemical and biological properties of the isoenzymes ADA1 and ADA2 as well as their usefulness in diagnostic of many diseases were described.