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Urodynamic patterns in infants with normal lower urinary tracts or primary vesico-ureteric reflux
C K Yeung1, M L Godley, H K Dhillon
1Department of Surgery, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin.
British Journal of Urology
|April 2, 1998
Summary
Infants with primary vesico-ureteric reflux (VUR) show significantly abnormal bladder function, particularly males. These findings suggest VUR may influence bladder development and persistence.
Area of Science:
- Pediatric Urology
- Urodynamics
- Infant Bladder Function
Background:
- Vesico-ureteric reflux (VUR) is a common condition in infants.
- Understanding bladder function in infants with VUR is crucial for management.
- Previous studies have not fully elucidated the urodynamic patterns in this population.
Purpose of the Study:
- To compare bladder function in infants diagnosed with primary VUR against those with normal lower urinary tracts.
- To identify specific urodynamic abnormalities associated with primary VUR in infants.
Main Methods:
- A comparative study involving 42 infants with VUR (grades III-V) and 21 controls without VUR.
- Urodynamic monitoring was performed using suprapubic catheters after a minimum of 24 hours.
- Three or more natural filling and voiding cycles were analyzed.
Main Results:
- 57% of infants with VUR exhibited abnormal urodynamic patterns, compared to none in the control group.
- Abnormal patterns included detrusor instability, inadequate voiding, dyssynergic patterns, and obstructive patterns, predominantly in males.
- Infants with VUR showed increased post-void residual volumes and higher voiding pressures.
Conclusions:
- A significant association exists between abnormal urodynamic variables and primary VUR in young infants, especially males.
- These findings may impact current understanding of VUR genesis and persistence.
- Urodynamic assessment is valuable in evaluating infants with primary VUR.