Related Experiment Videos
Early stages in male germ cell differentiation in the mouse. Review article
R Anderson1, M Garcia-Castro, J Heasman
1Department of Cell Biology and Neuroanatomy, University of Minnesota School of Medicine, Minneapolis 55455, USA.
Abstract:
Primordial germ cells arise during gastrulation and migrate from the hindgut into the gonad primordium during early organogenesis. In this article, we discuss factors that control migration, proliferation and targeting of the PGCs. In particular we discuss how changes in adhesiveness control germ cell positioning in the gonad, and the molecules involved.