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Plasminogen/plasminogen activator and growth factor activation
D B Rifkin1, P E Gleizes, J Harpel
1Department of Cell Biology, New York University Medical Center, NY 10016, USA.
Abstract:
The plasminogen/plasminogen activator system is widely used in extracellular proteolysis. In this review the involvement of this system in tumour invasion, cell migration, growth factor presentation and inhibition of angiogenesis are discussed.