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Cloning and sequencing of equine transforming growth factor-beta 1 (TGF beta-1) cDNA
M N Penha-Goncalves1, D E Onions, L Nicolson
1Department of Veterinary Pathology, University of Glasgow Veterinary School, Scotland, UK.
DNA Sequence : the Journal of DNA Sequencing and Mapping
|January 1, 1997
Abstract:
Transforming growth factor beta (TGF-beta) belongs to a family of peptide growth factors which control critical stages of cell proliferation and differentiation. We report the cloning and sequencing of the cDNA for TGF-beta type 1 isoform of the horse. The predicted mature equine TGF beta-1 peptide is 112 amino acids in length and exhibits 99% identity to mature human TGF beta-1.