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[Gene therapy]

L Rodríguez-Fragoso1

  • 1Departamento de Gastroenterología, Instituto Nacional de la Nutrición Salvador Zubirán, México, D.F.

Revista De Investigacion Clinica; Organo Del Hospital De Enfermedades De La Nutricion
|April 4, 1998
PubMed
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Gene therapy offers revolutionary treatments for diseases by delivering genes to cells. While significant progress has been made, overcoming technical challenges in gene delivery is crucial for safe and effective clinical application.

Area of Science:

  • Molecular Biology
  • Genetics
  • Medicine

Context:

  • Advances in understanding molecular mechanisms of disease pathogenesis.
  • Growing interest in gene-based therapies for human diseases.

Purpose:

  • To provide an overview of gene therapy, including current gene delivery techniques.
  • To highlight laboratory and clinical achievements in gene therapy.
  • To discuss the challenges and future directions of gene therapy.

Summary:

  • Gene therapy has evolved significantly, moving from science fiction to clinical application.
  • Current gene delivery methods and their advancements are detailed.
  • Examples of successful laboratory and clinical applications are presented.

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Impact:

  • Gene therapy is transforming medicine by addressing diseases at a molecular level.
  • Overcoming technical hurdles in gene delivery and cell transplantation is key for widespread clinical success.
  • Future technological developments will be critical for the safe and effective practice of gene therapy.