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[Pathogenesis of Alzheimer's disease]
1Departamento de Neurología, Clínica Universitaria, Facultad de Medicina, Universidad de Navarra.
Revista De Medicina De La Universidad De Navarra
|January 1, 1997
Abstract:
Alzheimer's disease (AD) is a multifactorial entity with a complex pathogeny. Recent findings on this subject are discussed in this article, centering mainly on genetic factors, cerebral ischemia and their association with the most typical histologic lesions in AD. Finally, a hypothetical model is proposed, in which beta-amyloid represents the key element.