Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Madopar: more than 20 years]

C Leiva1

  • 1Servicio de Neurología, Hospital General Universitario de Alicante, España.

Revista De Neurologia
|April 7, 1998
PubMed
Summary

Levodopa revolutionized Parkinson's disease treatment by addressing dopamine deficits. Despite its benefits, long-term use requires strategies to manage side effects and disease progression.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Improved recycling of a gasification fly ash: An integrated waste management approach within the framework of a Circular Economy.

Waste management (New York, N.Y.)·2024
Same author

Study of seashell waste recycling in fireproofing material: Technical, environmental, and economic assessment.

The Science of the total environment·2021
Same author

Environmental risks and mechanical evaluation of recycling red mud in bricks.

Environmental research·2020
Same author

A porous geopolymer based on aluminum-waste with acoustic properties.

Waste management (New York, N.Y.)·2019
Same author

Development of fly ash boards with thermal, acoustic and fire insulation properties.

Waste management (New York, N.Y.)·2015
Same author

Differential partitioning and speciation of Hg in wet FGD facilities of two Spanish PCC power plants.

Chemosphere·2011

Area of Science:

  • Neurochemistry and neuropharmacology discoveries underpin Parkinson's disease (PD) therapeutic strategies.
  • Understanding dopamine's role in motor control was crucial for developing PD treatments.

Context:

  • Parkinson's disease is characterized by a marked deficit of dopamine in specific brain regions.
  • Early research identified dopamine deficiency in PD patients, paving the way for targeted therapies.

Purpose:

  • To review key scientific milestones leading to levodopa's introduction for Parkinson's disease.
  • To assess the impact and evolution of levodopa therapy in managing PD.

Summary:

  • Levodopa therapy, introduced following discoveries in neurochemistry and dopamine deficits in PD, significantly improved patient outcomes and mortality.
  • While effective, levodopa does not halt disease progression and can cause side effects, necessitating ongoing treatment optimization.

Impact:

  • Levodopa remains the cornerstone of Parkinson's disease management, often used in conjunction with other therapies.
  • Further understanding of PD's etiology is required for a definitive cure.

Related Experiment Videos