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[Epidemiology and clinical framework of the ischemic pathology of the lower limbs]

M Bartolo1, A R Todini, P L Antignani

  • 1Divisione di Angiologia, Ospedale S. Camillo di Roma.

La Clinica Terapeutica
|April 7, 1998
PubMed

Insights

Atherosclerotic disease, a major health issue, includes intermittent claudication diagnosed via the ankle-arm blood pressure ratio (Winsor's index). Smoking, hypertension, and diabetes are key risk factors for peripheral arteriopathies.

Area of Science:

  • Cardiovascular Medicine
  • Vascular Surgery
  • Public Health

Background:

  • Atherosclerotic disease poses a significant health challenge in developed nations.
  • Intermittent claudication is a key manifestation of peripheral artery disease.

Purpose of the Study:

  • To review diagnostic methods for intermittent claudication.
  • To identify primary risk factors for peripheral arteriopathies.
  • To highlight mortality causes and risk modifiers in atherosclerotic disease.

Main Methods:

  • Utilized the Rose's questionnaire for intermittent claudication diagnosis.
  • Employed the ankle-arm blood pressure ratio (Winsor's index) as the current diagnostic standard.
  • Reviewed epidemiological data on incidence and risk factors.

Main Results:

  • Incidence of intermittent claudication varies: 0.4%-14.4% (Rose's questionnaire) vs. 4.2%-35% (Winsor's index).
  • Key risk factors identified: smoking, hypertension, and diabetes.
  • Myocardial infarction is the leading cause of death; co-existing coronary or cerebral arterial disease increases risk.

Conclusions:

  • The Winsor's index offers a higher incidence range for intermittent claudication compared to the Rose's questionnaire.
  • Aggressive management of smoking, hypertension, and diabetes is crucial for preventing peripheral arteriopathies.
  • Awareness of risk factors and associated pathologies is vital for reducing mortality from atherosclerotic disease.

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