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Granulocytic ehrlichiosis in tick-immune guinea pigs

S Das1, K Deponte, N L Marcantonio

  • 1Department of Internal Medicine, Yale University, New Haven, Connecticut 06520-8031, USA.

Infection and Immunity
|April 7, 1998
PubMed

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Rocky Mountain Spotted Fever (RMSF) is a severe tick-borne illness caused by Rickettsia rickettsii, a Gram-negative, coccobacillary bacterium. This pathogen is an obligate intracellular parasite, requiring a host cell for replication. Transmission occurs through the bite of an infected tick. In the United States, the most important vectors are Dermacentor variabilis (American dog tick) and Dermacentor andersoni (Rocky Mountain wood tick), though other tick species may also serve as vectors.