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Annular atrophic lichen planus and Sneddon's syndrome
D Lipsker1, J C Piette, J L Laporte
1Service de Médecine Interne, Hôpital Pitié-Salpëtrière, Paris, France.
Dermatology (Basel, Switzerland)
|January 1, 1997
Summary
This case report details a patient with two rare conditions: annular atrophic lichen planus (AALP) and Sneddon
Area of Science:
- Dermatology and Neurology
- Rare disease research
- Vasculopathy and connective tissue disorders
Background:
- Sneddon's syndrome (SNS) is characterized by livedo racemosa and cerebrovascular disease.
- Annular atrophic lichen planus (AALP) is an extremely rare variant of lichen planus.
- Both conditions may involve abnormalities in elastic tissue metabolism or structure.
Observation:
- A patient presented with concurrent AALP and SNS.
- The patient exhibited digital nodules with histological features suggesting SNS vasculopathy, a novel finding.
- This represents the third reported case of AALP and a rare instance of SNS.
Findings:
- The co-occurrence of AALP and SNS in a single patient.
- Histopathological evidence of vasculopathy in digital nodules associated with SNS.
- Postulated shared pathomechanisms involving elastic tissue degradation in both diseases.
Implications:
- Highlights the potential for overlapping pathologies in rare connective tissue and vascular disorders.
- Suggests further investigation into elastic tissue abnormalities in SNS and AALP.
- Contributes to the understanding of rare disease associations and their clinical manifestations.