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Updated: Aug 4, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
Methotrexate induced pericarditis and pericardial effusion in psoriatic patient
P Palungwachira1, P Palungwachira, P Laohathai
1Family Medicine Department, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Abstract:
We describe a 62-year-old woman with Psoriasis who presented as Methotrexate-induced pericarditis and pericardial effusion. Aspiration of the pericardium was required and the patient made a satisfactory recovery. At six-months follow-up, she remained well, psoriasis plaques was controlled by topical crude coal tar and topical corticosteroid. These complications are extremely rare, but have been described as isolated phenomena associated with methotrexate therapy.
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