Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Lipids in biliary lithogenesis

V Singh1, S A Zaidi, V S Singh

  • 1Department of Biochemistry, L.L.R.M. Medical College, Meerut, India.

JPMA. the Journal of the Pakistan Medical Association
|April 8, 1998
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Effect of <i>Calotropis procera</i> (madar) and amprolium supplementation on parasitological parameters of broilers during mixed <i>Eimeria</i> species infection.

Veterinary world·2017
Same author

Serum apolipoproteins in the patients of myocardial infarction in different age groups.

Indian journal of clinical biochemistry : IJCB·2012
Same author

Hydrochemical analysis to evaluate the seawater ingress in a small coral island of India.

Environmental monitoring and assessment·2011
Same author

A study of peripheral T-Lymphocytes in alopecia areata.

Indian journal of dermatology, venereology and leprology·2010
Same author

A study of immunoglobulins and complements (C3 & C4) in alopecia areata.

Indian journal of dermatology, venereology and leprology·2010
Same author

Assessment of seawater impact using major hydrochemical ions: a case study from Sadras, Tamilnadu, India.

Environmental monitoring and assessment·2010
Same journal

Predictors of Altmetric Score in Top-Cited Orthopaedic Articles: A Bibliometric Analysis.

JPMA. The Journal of the Pakistan Medical Association·2026
Same journal

Carbon footprint of waste generated in orthopaedic cases in Pakistan: a pilot descriptive study.

JPMA. The Journal of the Pakistan Medical Association·2026
Same journal

Enhancing quotation accuracy assessment with Chatpdf - a game-changer for a century-old conundrum.

JPMA. The Journal of the Pakistan Medical Association·2026
Same journal

Barriers to implementing simulation-based surgical training for improving quality and safety in developing countries: A short communication.

JPMA. The Journal of the Pakistan Medical Association·2026
Same journal

Intraoperative Adverse Event Reporting in Gastrointestinal Cancer Surgery: A Narrative Review on the Application of ClassIntra.

JPMA. The Journal of the Pakistan Medical Association·2026
Same journal

The Impact of Mortality and Morbidity Meetings on Quality Improvement and Patient Safety.

JPMA. The Journal of the Pakistan Medical Association·2026
See all related articles

Gallstone formation is linked to higher levels of low-density lipoprotein cholesterol (LDLc) and triglycerides (TG), and lower levels of high-density lipoprotein cholesterol (HDLc). These lipoprotein profiles significantly correlate with gallstone presence.

Area of Science:

  • Biochemistry
  • Gastroenterology
  • Lipid Metabolism

Background:

  • Gallstones are a common gastrointestinal condition.
  • Lipoprotein metabolism is implicated in gallstone pathogenesis.
  • Previous research suggests a link between cholesterol levels and gallstones.

Purpose of the Study:

  • To investigate the association between serum and biliary lipoproteins and gallstone disease.
  • To determine the specific roles of LDLc, HDLc, TG, and VLDLc in gallstone formation.

Main Methods:

  • Measurement of serum and biliary lipoproteins, total cholesterol (Tc), and triglycerides (TG) in patients with and without gallstones.
  • Statistical analysis to identify correlations and significant differences between groups.

Related Experiment Videos

Main Results:

  • Significantly higher serum and biliary LDLc, TG, and Tc in patients with gallstones compared to controls (P < 0.001).
  • Significantly lower HDLc levels in patients with gallstones (P < 0.001).
  • No significant difference in VLDLc between the groups.
  • Strong positive correlations found between LDLc and HDLc with gallstone presence (r = +.67 and r = +.56, respectively).

Conclusions:

  • Serum HDLc and LDLc play critical roles in gallstone formation, more so than total cholesterol and triglycerides.
  • Altered lipoprotein profiles, particularly LDLc and HDLc, are strongly associated with gallstone disease.