Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The waveguide Mach-Zender interferometer as atrazine sensor

E F Schipper1, S Rauchalles, R P Kooyman

  • 1MESA Research Institute, Department of Applied Physics, University of Twente, Enschede, The Netherlands.

Analytical Chemistry
|April 8, 1998
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Outcome of the geriatric head and neck cancer patient].

HNO·2026
Same author

Exoscopic-assisted head and neck surgery: a comparative evaluation optimizing ergonomics and workflow.

Journal of robotic surgery·2025
Same author

Bacterial lipopolysaccharide modulates immune response in the colorectal tumor microenvironment.

NPJ biofilms and microbiomes·2023
Same author

[Typical emergencies in otorhinolaryngology-a monocentric analysis of the seasonal course].

HNO·2022
Same author

[Oncologic follow-up in head and neck cancer patients].

HNO·2022
Same author

Performance of microvascular anastomosis with a new robotic visualization system: proof of concept.

Journal of robotic surgery·2021
Same journal

Machine Learning-Assisted Label-Free SERS Decoding of Mitochondrial Molecular Dynamics in Ovarian Granulosa Cells during Aging.

Analytical chemistry·2026
Same journal

Revealing the Regulatory Interplay of NHE1 mRNA and Na<sup>+</sup> in Cancer Cells Using a DNA Nanosensor.

Analytical chemistry·2026
Same journal

Towards Cellular Resolution of Tryptic Peptides in Tissue Sections by MALDI MS Imaging: A Focus on Enzyme Application and Reproducibility.

Analytical chemistry·2026
Same journal

Bioinspired Bilayer Hydrogel Colorimetric Sensor Array for Low-Temperature Food Freshness Analysis.

Analytical chemistry·2026
Same journal

Quartz Crystal Microbalance-Based Point-of-Care Testing Systems: Principles, Device Design, and Applications.

Analytical chemistry·2026
Same journal

Heterojunction Gate-Empowered OPECT Aptasensing: A Valid Protocol for Realizing High Current Gain at Low Electron Donor Dependency.

Analytical chemistry·2026
See all related articles

A novel Mach-Zehnder waveguide sensor enables rapid, on-line monitoring of immunoreactions, achieving sensitive detection of environmental contaminants like atrazine within 10 minutes.

Area of Science:

  • Analytical Chemistry
  • Environmental Science
  • Biotechnology

Background:

  • Immunoanalytical techniques are crucial for detecting substances.
  • Mach-Zehnder waveguide sensors offer high sensitivity for real-time analysis.
  • Environmental monitoring requires rapid and accurate detection methods.

Purpose of the Study:

  • To develop and validate a Mach-Zehnder waveguide sensor for fast on-line monitoring of immunoreactions.
  • To assess the sensor's capability for environmental probing, specifically for detecting low concentrations of atrazine.
  • To compare the sensor's performance with established methods like ELISA.

Main Methods:

  • Utilizing immunoanalytical techniques integrated with a Mach-Zehnder waveguide sensor.
  • Employing an inhibition technique for the detection of atrazine.

Related Experiment Videos

  • Implementing a dynamic slope method for rapid measurement completion.
  • Conducting parallel measurements with Enzyme-Linked Immunosorbent Assays (ELISAs) for comparison.

    • Main Results:

    • The developed sensor system allows for fast on-line monitoring of immunoreactions.
    • Low concentrations of atrazine (around 100 ng/L, the EC limit) were measured with high sensitivity.
    • A complete measurement cycle, including sample analysis, was achieved within 10 minutes.
    • Sensor measurements demonstrated comparable sensitivity and error margins to parallel ELISAs.

    Conclusions:

    • The Mach-Zehnder waveguide sensor is a viable tool for rapid, on-line immunoanalytical monitoring.
    • The sensor system shows significant potential as an environmental probe for detecting contaminants like atrazine.
    • The developed method offers a fast and sensitive alternative to traditional methods such as ELISA for specific applications.