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Premonitory and prodromal symptoms in cluster headache

J N Blau1, H O Engel

  • 1City of London Migraine Clinic, UK.

Cephalalgia : an International Journal of Headache
|April 9, 1998
PubMed
Summary

Cluster headache warning symptoms manifest as short-term prodromes before attacks or long-term premonitory symptoms preceding cluster periods. Understanding these distinct warning patterns is crucial for managing cluster headache.

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Area of Science:

  • Neurology
  • Neuroscience
  • Pain Medicine

Background:

  • Cluster headache is a debilitating neurological disorder characterized by severe unilateral head pain.
  • Understanding the pre-attack warning symptoms of cluster headache is essential for diagnosis and treatment.

Purpose of the Study:

  • To investigate the characteristics of warning symptoms in patients experiencing cluster headache attacks during waking hours.
  • To differentiate between prodromal symptoms and premonitory symptoms in cluster headache.

Main Methods:

  • A study was conducted on 150 patients diagnosed with cluster headache.
  • Warning symptoms were categorized based on their temporal relationship to the onset of pain or cluster periods.
  • Data was collected focusing on attacks occurring during waking hours.

Main Results:

  • Two distinct types of warning symptoms were identified: prodromes and premonitory symptoms.
  • Prodromes, occurring minutes before pain, were reported by 122 patients.
  • Premonitory symptoms, preceding cluster periods by days to weeks, were reported by 12 patients.

Conclusions:

  • Cluster headache warning symptoms exhibit distinct temporal patterns, aiding in understanding the condition's pathophysiology.
  • The findings suggest potential implications for both the understanding of cluster headache pathogenesis and the development of targeted therapeutic strategies.

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