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Identification and characterization of a myomodulin-like peptide in the leech
Y Wang1, D A Price, C L Sahley
1Department of Biological Sciences, Purdue University, West Lafayette, IN 47907, USA.
Peptides
|April 9, 1998
Abstract:
A novel myomodulin-like peptide, GMGALRLamide, has been purified and sequenced from extracts of 1000 medicinal leech nerve cords. Synthetic leech myomodulin-like peptide blocked the specific staining pattern of leech ganglia by the antiserum against Aplysia myomodulin A PMGMLRLamide. Moreover, the synthetic leech myomodulin-like peptide GMGALRLamide showed identical neuronal modulation effect on the giant leech Retzius cell compare to that by the synthetic Aplysia myomodulin A PMGMLRLamide.