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Vesicular mycosis fungoides
S R McBride1, M G Dahl, D N Slater
1Department of Dermatology, Royal Victoria Infirmary, Newcastle upon Tyne, U.K.
The British Journal of Dermatology
|April 16, 1998
Summary
Blistering is an unusual presentation of mycosis fungoides (MF). This aggressive MF case featured prominent blistering, delaying diagnosis and leading to a fatal outcome within a year.
Area of Science:
- Dermatology
- Oncology
- Pathology
Background:
- Mycosis fungoides (MF) is the most common type of cutaneous T-cell lymphoma.
- Vesicle formation is not a typical histopathological feature of MF.
Observation:
- A rare case of MF presented with prominent histopathological vesicle formation.
- This unusual presentation led to a delay in diagnosis.
- The patient's disease followed an aggressive clinical course.
Findings:
- The MF case exhibited significant blistering, mimicking other blistering disorders.
- Aggressive disease progression was noted, with death occurring within one year.
- Unusual late-stage involvement of the tongue with MF occurred.
Implications:
- Highlights the importance of considering MF in blistering disorders, even with atypical features.
- Underscores the potential for aggressive disease courses in MF.
- Suggests MF can present with diverse and unusual clinical and pathological manifestations.