Postoperative hypoglycaemia in small children

British Medical Journal
|August 28, 1976
PubMed

Insights

Postoperative hypoglycemia occurred in 6 of 57 young children despite fluid administration. Early feeding, especially milk, is recommended for small children after surgery to prevent low blood sugar.

Area of Science:

  • Pediatric Surgery
  • Pediatric Anesthesiology
  • Pediatric Critical Care

Background:

  • Postoperative hypoglycemia is a potential complication in young children.
  • Current fluid management strategies may not consistently prevent hypoglycemia.

Purpose of the Study:

  • To investigate the incidence of hypoglycemia in children under 4 years old during postoperative recovery.
  • To identify risk factors for predicting postoperative hypoglycemia.
  • To provide recommendations for preventing postoperative hypoglycemia.

Main Methods:

  • Observational study of 57 children under 4 years old undergoing various surgical procedures.
  • Monitoring for hypoglycemic events during the postoperative recovery period.
  • Analysis of patient age and weight-for-age as potential predictors.

Main Results:

  • Six out of 57 children (10.5%) developed hypoglycemia postoperatively.
  • Neither age nor weight-for-age could reliably predict children at risk.
  • Intravenous or oral fluid administration did not always prevent hypoglycemia.

Conclusions:

  • Postoperative hypoglycemia is a significant concern in young surgical patients.
  • Early initiation of oral feeding, preferably with milk, is crucial for preventing hypoglycemia in small children after surgery.

Related Concept Videos

Pathophysiology of Diabetes01:20

Pathophysiology of Diabetes

Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility, suggesting a...
Insulin: Dosing Regimen and Adverse Effects01:16

Insulin: Dosing Regimen and Adverse Effects

Insulin-replacement therapy usually includes both long-acting insulin (basal) and short-acting insulin (to cater to postprandial needs). In a diverse group of type 1 diabetes patients, the average daily insulin dose is typically 0.5-0.7 units/kg body weight. However, obese patients and pubertal adolescents may need more due to insulin resistance.
The basal dose constitutes about 40%-50% of the total daily dose, with the rest as premeal insulin. The mealtime insulin dose should mirror...
Oral Hypoglycemic Agents: Glinides01:06

Oral Hypoglycemic Agents: Glinides

Repaglinide (Prandin) and Nateglinide (Starlix), known as glinides, are oral insulin secretagogues that stimulate insulin release from pancreatic β cells by closing the ATP-sensitive potassium channels (KATP channel). Repaglinide controls insulin release from pancreatic β cells by managing potassium efflux. It shares two binding sites with sulfonylureas and also has a unique site, indicating overlapping mechanisms of action. With a rapid onset and a 4-7 hour duration, it effectively manages...
Oral Hypoglycemic Agents: α-Glucosidase Inhibitors01:19

Oral Hypoglycemic Agents: α-Glucosidase Inhibitors

α-glucosidase inhibitors, including acarbose (Precose), miglitol (Glyset), and voglibose (Voglib) (primarily available in Asia), are drugs that control blood sugar levels by delaying the digestion of starch and disaccharides. They achieve this by inhibiting α-glucosidase enzymes in the intestine, which slow the absorption of carbohydrates in the intestine, which in turn leads to a prolonged release of the glucoregulatory hormone GLP-1 from intestinal L-cells.
Acarbose and miglitol are typically...
Hypoglycemia and Glucagon01:15

Hypoglycemia and Glucagon

Without prolonged fasting, healthy individuals maintain blood glucose levels above 3.5 mM due to a well-adapted neuroendocrine counterregulatory system that effectively prevents acute hypoglycemia, a potentially life-threatening condition. The primary clinical scenarios for hypoglycemia encompass diabetes treatment, inappropriate production of endogenous insulin or insulin-like substances by tumors, and the use of glucose-lowering agents in non-diabetic individuals. Notably, hypoglycemia in the...
Hypoglycemia01:26

Hypoglycemia

Hypoglycemia is a blood glucose level below 70 mg/dL. It commonly occurs in individuals using insulin or insulin-secreting drugs, but may also arise in non-diabetic conditions. People with type 1 diabetes are at the highest risk because they depend on exogenous insulin. People with type 2 diabetes are also at risk, especially when treated with insulin or medications such as sulfonylureas, which increase insulin release regardless of blood glucose levels. It develops when insulin levels exceed...