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Tissue banking programmes in Europe

E S Kalter1, T M de By

  • 1Bio Implant Services Foundation, Leiden, The Netherlands.

British Medical Bulletin
|January 1, 1997
PubMed
Summary

European organ centres and tissue banks facilitate organ and tissue transplantation by managing donor screening, procurement, processing, and allocation. This review examines optimal practices for tissue banking and donor screening in Europe to meet clinical needs.

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Area of Science:

  • Transplantation immunology
  • Tissue engineering
  • Public health policy

Background:

  • Organ centres and tissue banks in Europe, like Bio Implant Services (BIS) and Eurotransplant, are crucial intermediaries in the organ and tissue transplantation process.
  • They manage donor screening, procurement, and facilitate allocation according to established expert guidelines.
  • The most commonly donated tissues include corneas, heart valves, bone, soft tissue, and skin.

Purpose of the Study:

  • To review optimal serological screening of donors for tissue and organ transplantation in Europe.
  • To assess current tissue banking practices in relation to clinical demand and availability.
  • To evaluate the organizational structure, processing, preservation, and quality standards of European tissue banks.

Main Methods:

  • Review of existing literature and practices in European tissue banking and donor screening.
  • Analysis of data on transplantable tissue volumes, clinical need, and the number and organization of tissue banks.
  • Examination of explantation, processing, preservation methods, and quality standards.

Main Results:

  • The article reviews the intermediary roles of organ centres and tissue banks in the donation-to-transplantation pathway.
  • It examines the allocation of scarce tissues based on expert committee rules.
  • Key tissue types and current banking practices are discussed in the context of clinical needs and available resources.

Conclusions:

  • Optimal donor screening and tissue banking are essential for meeting the clinical demand for transplantation in Europe.
  • The organizational level and methods employed by tissue banks significantly impact the availability and quality of transplantable tissues.
  • Continuous evaluation of quality standards and adaptation to new developments are necessary for efficient tissue banking.

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