Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Automated image analysis for bladder cancer

H G van der Poel, J A Witjes, J A Schalken

    Urological Research
    |April 16, 1998
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Microvessel density: correlation between contrast ultrasonography and histology of prostate cancer.

    European urology·2001
    Same author

    Can biological markers replace cystoscopy? An update.

    Current opinion in urology·2001
    Same author

    Posterior tibial nerve stimulation as neuromodulative treatment of lower urinary tract dysfunction.

    The Journal of urology·2001
    Same author

    Long-term followup of randomized transurethral microwave thermotherapy versus transurethral prostatic resection study.

    The Journal of urology·2001
    Same author

    Branching activity in the human prostate: a closer look at the structure of small glandular buds.

    European urology·2001
    Same author

    Intra-prostatic vasculature studies: can they predict the outcome of transurethral microwave thermotherapy for the management of bladder outflow obstruction?

    The Prostate·2001
    Same journal

    Erratum to: Is routine ureteral stenting necessary after uncomplicated ureteroscopic lithotripsy for lower ureteral stones larger than 1 cm?

    Urological research·2017
    Same journal

    2002 30(th) Munich Endourological Symposium 10-11 October 2002.

    Urological research·2014
    Same journal

    Ellagica acid inhibits arylamine N-acetyltransferase activity and DNA adduct formation in human bladder tumor cell lines (T24 and TSGH 8301).

    Urological research·2014
    Same journal

    Biomolecular mechanism of urinary stone formation involving osteopontin.

    Urological research·2012
    Same journal

    Renal tubular epithelial cell injury, apoptosis and inflammation are involved in melamine-related kidney stone formation.

    Urological research·2012
    Same journal

    Role of 1 week of antibiotic prophylaxis before percutaneous nephrolithotomy.

    Urological research·2012
    See all related articles

    Light microscopy image analysis objectively assesses cell and nuclear morphology changes during cancer development. These methods aid in diagnosing bladder cancer and predicting patient prognosis, with systems developed for clinical use.

    Area of Science:

    • Oncology
    • Pathology
    • Biomedical Imaging

    Background:

    • Cancer development involves genetic and epigenetic alterations leading to observable morphological changes.
    • Light microscopic image analysis offers an objective method to evaluate cellular and nuclear morphology.
    • The dedifferentiation process in cancer is complex, often involving multiple genetic hits.

    Discussion:

    • Image analysis techniques have demonstrated significant value in assessing malignancy within bladder cancer samples.
    • The complexity of morphological changes correlates with the multi-hit nature of cancer dedifferentiation.
    • Clinically applicable systems utilizing image analysis have been developed for urothelial cell carcinoma diagnosis.

    Key Insights:

    • Objective assessment of cellular and nuclear morphology via light microscopy aids cancer diagnosis.

    Related Experiment Videos

  • Image analysis systems can effectively diagnose urothelial cell cancer and predict patient prognosis.
  • The multi-hit nature of cancer dedifferentiation is reflected in complex morphological changes detectable by image analysis.

    • Outlook:

    • Further integration of these image analysis systems into daily clinical practice is anticipated.
    • The role of these diagnostic and prognostic tools in routine pathology workflows requires further definition.
    • Continued development aims to refine the clinical applicability of image analysis in bladder cancer management.