Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Hürthle cell tumors

N Hillman1, D Hardisson, L Herranz

  • 1Department of Endocrinology, Hospital La Paz, Autonoma University of Madrid, Spain.

Annales De Medecine Interne
|January 1, 1997
PubMed
Summary

This study analyzed Hürthle cell neoplasms (HCT), finding no reliable clinical or morphological predictors for recurrence. Further research is needed to understand the controversial behavior of these thyroid tumors.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Executive summary of the consensus document on management of the transition of patients with inborn errors of intermediary metabolism.

Revista clinica espanola·2026
Same author

Clinical characteristics and management of Spanish adult patients with phenylketonuria.

Revista clinica espanola·2025
Same author

Remote assessment of the Penn computerised neurocognitive battery in individuals with 22q11.2 deletion syndrome.

Journal of intellectual disability research : JIDR·2024
Same author

OSNA Total Tumor Load for the Prediction of Axillary Involvement in Breast Cancer Patients: Should We use Different Thresholds According to the Intrinsic Molecular Subtype? MOTTO Study.

Clinical pathology (Thousand Oaks, Ventura County, Calif.)·2023
Same author

Bevacizumab in recurrent ovarian cancer: could it be particularly effective in patients with clear cell carcinoma?

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·2020
Same author

Toe Brachial Pressure Index as Alternative Method to Correlate Arteriosclerotic Disease in Type 2 Diabetes.

The Journal of the Association of Physicians of India·2019

Area of Science:

  • Endocrinology
  • Surgical Pathology
  • Oncology

Background:

  • Hürthle cell neoplasms (HCT) present diagnostic challenges due to variable behavior.
  • Distinguishing benign from malignant HCT is crucial for patient management.

Purpose of the Study:

  • To profile Hürthle cell neoplasms (HCT) clinicopathologically.
  • To identify differences in clinical and morphological features among benign, malignant, and indeterminate HCT.
  • To assess the predictive value of features for HCT behavior.

Main Methods:

  • Retrospective review of 25 HCT cases diagnosed between 1981-1996.
  • Histological classification based on invasion, atypia, necrosis, and growth patterns.
  • Evaluation of clinical parameters and patient follow-up data.

Main Results:

  • HCT distribution: 52% benign, 40% malignant, 8% indeterminate.
  • Four local recurrences (20%) observed, with a trend (p=0.15) but no statistical significance.
  • One metastatic case resulted in tumor-related death.
  • No significant clinical or histological differences identified between groups regarding recurrence, except for invasion and therapy.

Conclusions:

  • No specific clinical or morphological parameter reliably predicts recurrence in HCT.
  • The biological behavior of Hürthle cell neoplasms remains controversial and requires further investigation.

Related Experiment Videos