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[Bacteriological study of purulent nasopharyngitis in children in Senegal]
Insights
In Senegal, Streptococcus pneumoniae, Haemophilus influenzae, and Streptococcus pyogenes were the most common bacteria found in children with acute purulent rhinopharyngitis. These findings highlight key pathogens and their antibiotic resistance profiles in the region.
Area of Science:
- Microbiology
- Pediatrics
- Epidemiology
Context:
- Acute purulent rhinopharyngitis is a common childhood illness.
- The primary bacterial pathogens causing rhinopharyngitis vary geographically.
- Understanding local bacterial flora is crucial for effective treatment.
Purpose:
- To determine the frequency of pathogenic bacteria in children with acute purulent rhinopharyngitis in Senegal.
- To characterize the serotypes and antibiotypes of isolated bacteria.
- To assess antibiotic susceptibility patterns.
Summary:
- A study of 93 Senegalese children (1 month to 7 years) with purulent rhinopharyngitis identified Streptococcus pneumoniae (28%), Group C streptococci (19%), Haemophilus influenzae (15.5%), Streptococcus pyogenes (9.5%), and Staphylococcus aureus (8%) as predominant isolates.
- Streptococcus pneumoniae and Streptococcus pyogenes showed no penicillin resistance. Haemophilus influenzae strains were largely susceptible to ampicillin (81%) and chloramphenicol (96%).
- Infants aged 6-18 months were most affected. Streptococcus pneumoniae serogroups 6, 19, and 23 were identified, with only three encapsulated Haemophilus influenzae type b strains.
Impact:
- Provides essential epidemiological data on pediatric rhinopharyngitis pathogens in Senegal.
- Informs targeted therapeutic strategies and antibiotic stewardship.
- Contributes to the understanding of bacterial serotypes and resistance patterns in West Africa.
Background:
S pneumoniae, H influenzae and M catarrhalis are the main bacteria isolated from rhinopharynx in Europe. The purpose of this work was to study the frequency of potential pathogenic bacteria isolated from acute purulent rhinopharyngitis among children in Senegal.
Population And Methods:
Ninety-three children from one month to 7-years old suffering from purulent rhinopharyngitis were recruited from April 1 to July 1996. The withdrawal samples were taken from the cavum with a swab which was immediately immersed in an agar shipping medium. Bacteria's grouping and serotyping were made by immunoagglutination. A standard antibiogram was made for all isolates and furthermore the minimal inhibitory concentration (MIC) were determined for S pneumoniae.
Results:
Two hundred bacterial strains were isolated: S pneumoniae 28% (60% of the children), C group streptococci: 19% (41% of the children), H influenzae: 15.5% (33% of the children), S pyogenes: 9.5% (20% of the children), S aureus: 8% (17% of the children) and M catarrhalis: 6% (13% of the children). The other isolates were: B and D groups streptococci, P aeruginosa and Klebsiella spp. S pnuemoniae strains belonged to serogroups 6, 19 and 23. Only three strains of H influenzae were capsulated (serotype b). Infants aged from 6 to 18 months were the most affected. No resistance to penicillin was observed for S pneumoniae and S pyogenes. Ampicillin (81%) and chloramphenicol (96%) both inhibited the majority of H influenzae strains.
Conclusions:
This descriptive bacterial epidemiology study of children's rhinopharynx's flora in Senegal allowed us to identify three major pathogenic germs: S pneumoniae, H influenzae and S pyogenes contributing to a better knowledge of these microorganisms' serotypes, biotypes and antibiotypes.