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Primary pulmonary sarcoma with morphologic features of biphasic synovial sarcoma: a case report
1Department of Diagnostic Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Journal of Korean Medical Science
|April 16, 1998
Summary
A rare biphasic synovial sarcoma occurred primarily in the lung of a 36-year-old woman. This pulmonary sarcoma case, confirmed by histology and immunology, showed no recurrence 15 months post-surgery.
Area of Science:
- Oncology
- Pathology
- Surgical Oncology
Background:
- Pulmonary sarcomas are rare neoplasms.
- Synovial sarcoma typically arises in soft tissues, rarely in the lung.
- Distinguishing primary pulmonary sarcomas from metastatic disease is crucial.
Observation:
- A 36-year-old woman presented with an unusual primary pulmonary tumor.
- The tumor exhibited histological, immunological, and ultrastructural characteristics of biphasic synovial sarcoma.
- Microscopic examination revealed a mix of epithelial and spindle cells, positive for cytokeratin, epithelial membrane antigen (EMA), and vimentin.
Findings:
- The patient underwent a successful lobectomy for the pulmonary synovial sarcoma.
- Post-operative follow-up at 15 months showed no evidence of recurrence or metastasis.
- This case adds to the limited literature on primary pulmonary synovial sarcoma.
Implications:
- This report highlights the possibility of primary pulmonary synovial sarcoma.
- The distinct features of this neoplasm aid in differentiating it from other lung malignancies.
- Successful surgical management offers a favorable prognosis for this rare condition.