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Translocation of inserted foreign epitopes by a channel-forming protein

K S Jakes1, P K Kienker, S L Slatin

  • 1Department of Physiology and Biophysics, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA. jakes@aecom.yu.edu

Proceedings of the National Academy of Sciences of the United States of America
|May 16, 1998
PubMed
Summary

Bacterial toxins like colicin Ia can insert into lipid membranes. This study shows colicin Ia can translocate foreign protein sequences, suggesting a general protein translocation mechanism.

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