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[Does treatment with thrombocyte aggregation inhibitors modify kidney transplantation surgery?]
W Werner1, A Klemm, H Wunderlich
1Klinik und Poliklinik für Urologie, Friedrich-Schiller-Universität Jena.
Der Urologe. Ausg. A
|April 16, 1998
Summary
Aspirin treatment up to 100 mg daily is generally accepted for renal transplant patients, with most centers proceeding with surgery despite aspirin use. Elective surgery may benefit from a switch to heparin preoperatively.
Area of Science:
- Nephrology
- Cardiology
- Transplantation Medicine
Context:
- Aspirin's influence on hemostasis remains debated, particularly in transplant patients.
- Uncertainty exists regarding optimal aspirin dosage and medication changes in emergency surgical settings.
Purpose:
- To analyze therapeutic approaches in German transplantation centers regarding aspirin use.
- To discuss transplant suitability, dosage, and hemostatic effects of aspirin in relation to existing literature.
Summary:
- Most German transplantation centers (92.11%) perform surgeries on patients taking aspirin.
- An increased bleeding tendency is observed in 34.2% of centers, but increased mortality has not been reported.
- Aspirin dosage up to 100 mg daily is commonly accepted; refusal rates are low (7.89%).
Impact:
- Correctly indicated aspirin treatment (up to 100 mg daily) does not contraindicate renal transplantation.
- Preoperative medication change to heparin is recommended for elective surgeries in patients on aspirin.