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Ecstasy: 3,4-methylenedioxymethamphetamine (MDMA)

B H Morimoto1, S Lovell, B Kahr

  • 1AMUR Pharmaceuticals, San Carlos, CA 94070, USA. morimoto@amur.com

Acta Crystallographica. Section C, Crystal Structure Communications
|April 16, 1998
PubMed
Summary
This summary is machine-generated.

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The crystal structure of 3,4-methylenedioxymethamphetamine hydrochloride, also known as ecstasy or MDMA, was determined using X-ray diffraction. This research provides foundational crystallographic data for this psychoactive compound.

Area of Science:

  • Crystallography
  • Structural Chemistry
  • Pharmacology

Background:

  • 3,4-methylenedioxymethamphetamine (MDMA), commonly known as ecstasy, is a widely recognized psychoactive substance.
  • Understanding the precise molecular arrangement of MDMA is crucial for its pharmacological and toxicological study.

Purpose of the Study:

  • To determine the definitive crystal structure of 3,4-methylenedioxymethamphetamine hydrochloride.
  • To provide a detailed crystallographic analysis of MDMA for scientific reference.

Main Methods:

  • X-ray diffraction analysis was employed to elucidate the crystal structure.
  • Single crystals of 3,4-methylenedioxymethamphetamine hydrochloride were subjected to X-ray analysis.

Main Results:

Related Experiment Videos

  • The complete three-dimensional crystal structure of N-methyl-1-[3,4-(methylenedioxy) phenyl]-2-aminopropane hydrochloride (MDMA.HCl) was successfully determined.
  • Detailed atomic coordinates and bond parameters were obtained.

Conclusions:

  • The crystal structure determination provides essential data on the solid-state conformation of MDMA.
  • This structural information serves as a basis for further research into MDMA's interactions and properties.