Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Evaluating asymptomatic patients with mildly elevated liver enzymes

Z M Younossi1

  • 1Department of Gastroenterology, Cleveland Clinic, USA.

Cleveland Clinic Journal of Medicine
|April 16, 1998
PubMed
Summary

Evaluating elevated liver enzymes in healthy individuals requires careful consideration. This review offers guidance on diagnosing liver enzyme abnormalities to avoid unnecessary tests and missed diagnoses.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Treatment of hepatitis C virus leads to economic gains related to reduction in cases of hepatocellular carcinoma and decompensated cirrhosis in Japan.

Journal of viral hepatitis·2018
Same author

Editorial: direct-acting antivirals significantly improve quality of life in patients with hepatitis C virus infection-Author's reply.

Alimentary pharmacology & therapeutics·2018
Same author

Hospice care in Medicare patients with primary liver cancer: the impact on resource utilisation and mortality.

Alimentary pharmacology & therapeutics·2018
Same author

Quality of life in adolescents with hepatitis C treated with sofosbuvir and ribavirin.

Journal of viral hepatitis·2017
Same author

Sofosbuvir and velpatasvir with or without voxilaprevir in direct-acting antiviral-naïve chronic hepatitis C: patient-reported outcomes from POLARIS 2 and 3.

Alimentary pharmacology & therapeutics·2017
Same author

Impact of ledipasvir/sofosbuvir on the work productivity of genotype 1 chronic hepatitis C patients in Asia.

Journal of viral hepatitis·2017

Area of Science:

  • Hepatology
  • Clinical Biochemistry
  • Primary Care Medicine

Background:

  • Elevated liver enzymes are common in asymptomatic individuals (1-4%).
  • Extensive testing poses risks and costs, while under-evaluation may miss treatable conditions.

Purpose of the Study:

  • To review causes of elevated liver enzymes.
  • To provide algorithms for evaluating abnormal liver enzyme values in apparently healthy patients.

Main Methods:

  • Literature review of causes for elevated aminotransferase, alkaline phosphatase, and gamma-glutamyl transferase.
  • Development of diagnostic algorithms for primary care.

Main Results:

  • Discussion of common and uncommon causes of liver enzyme elevation.
  • Presentation of structured approaches to patient evaluation.

Conclusions:

  • A balanced approach is needed to evaluate liver enzyme elevations.
  • Algorithms can guide primary care physicians in managing these findings effectively.

Related Experiment Videos