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A murine specific splicing variant of the acetylcholine receptor epsilon-subunit gene transcript
1Department of Anatomy and Structural Biology, University of Otago Medical School, Dunedin, New Zealand. kyoko.koishi@stonebow.otago.ac.nz
Biochimica Et Biophysica Acta
|April 16, 1998
Abstract:
The acetylcholine receptor (AChR) is an ion channel involved in signal transmission from motorneuron to skeletal muscle. We describe here a murine-specific splicing variant of the epsilon subunit of the AChR (epsilon s), which lacks exon 5 epsilon s has a truncated extracellular domain which may affect the physiological characteristics of the resulting AChR channel.