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Rasmussen encephalitis: complementary role of multitechnique neuroimaging

E Geller1, E N Faerber, A Legido

  • 1Department of Radiology, Allegheny University of the Health Sciences, St Christopher's Hospital for Children, Philadelphia, PA 19134, USA.

AJNR. American Journal of Neuroradiology
|April 16, 1998
PubMed
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Rasmussen encephalitis is a progressive brain inflammation. Neuroimaging aids early diagnosis and treatment to prevent cognitive decline.

Area of Science:

  • Neurology
  • Neuroinflammation
  • Neuroimaging

Background:

  • Rasmussen encephalitis is a rare, chronic inflammatory brain disease of unknown cause.
  • It leads to progressive cognitive decline, necessitating early diagnosis and intervention.
  • Current treatments include immunoactive agents and hemispherectomy.

Observation:

  • This study presents two biopsy-proven cases of Rasmussen encephalitis.
  • It highlights the role of combined neuroimaging techniques in diagnosis.
  • Magnetic resonance (MR) imaging, single-photon emission computed tomography (SPECT), and proton MR spectroscopy are discussed.

Findings:

  • Combined anatomic and functional neuroimaging can help focus diagnostic workup.
  • These techniques may expedite brain biopsy for definitive diagnosis.

Related Experiment Videos

  • The presented cases illustrate the utility of MR imaging, SPECT, and MR spectroscopy.

    • Implications:

    • Early and accurate diagnosis through advanced neuroimaging is crucial.
    • Timely intervention can potentially halt or slow cognitive decline.
    • This approach may improve patient outcomes in Rasmussen encephalitis.