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Accidental iron poisoning in childhood. Six cases including one fatality
Clinical Pediatrics
|September 1, 1976
Insights
Accidental iron poisoning in children can be life-threatening, even with treatment. This study highlights the severe risks associated with high serum iron concentrations in pediatric patients.
Area of Science:
- Pediatric Toxicology
- Environmental Health
Background:
- Accidental iron poisoning is a significant concern in pediatric healthcare.
- Iron-containing products are common household items, increasing exposure risk.
Observation:
- A review of cases between 1962 and 1973 at Massachusetts General Hospital identified six children with accidental iron poisoning.
- Two children experienced life-threatening intoxication, with serum iron levels surpassing their total iron-binding capacity.
Findings:
- One child with severe iron intoxication died despite receiving intensive supportive care and desferoxamine treatment.
- Elevated serum iron concentrations exceeding binding capacity are indicative of severe, potentially fatal poisoning.
Implications:
- Accidental iron poisoning, though infrequent, poses a critical risk of severe morbidity and mortality in children.
- Enhanced public awareness and safety measures regarding iron-containing products are crucial for preventing pediatric poisoning incidents.
Abstract:
Between 1962 and 1973, six children were admitted to the Massachusetts General Hospital because of accidental iron poisoning. Intoxication was life-threatening in two children whose serum iron concentrations exceeded their iron binding capacities. One of these patients died despite intensive supportive care and desferoxamine therapy. Although iron poisoning appears to be relatively uncommon, it can produce life-threatening and fatal intoxication in children.