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Castleman disease mimicking a hepatic neoplasm
R L Cirillo1, K M Vitellas, B R Deyoung
1Department of Diagnostic Radiology, Ohio State University, University Medical Center, Columbus, USA.
Clinical Imaging
|April 17, 1998
Summary
Castleman disease, a rare cause of lymph node enlargement, can occur outside the chest. This report details a unique case of hepatic Castleman disease mimicking a liver tumor.
Area of Science:
- Oncology
- Pathology
- Hepatology
Background:
- Castleman disease (angiofollicular hyperplasia) is a rare lymphoproliferative disorder.
- Typically presents as lymph node enlargement, predominantly in the thorax.
- Extrathoracic and hepatic presentations are exceptionally rare.
Observation:
- A case of Castleman disease localized to the porta hepatis is presented.
- The condition mimicked a hepatic neoplasm on initial presentation.
- This highlights a rare extrathoracic manifestation of the disease.
Findings:
- Histopathological examination confirmed Castleman disease in the hepatic porta.
- The clinical presentation and imaging findings were initially suggestive of a liver tumor.
- This case underscores the importance of considering rare differential diagnoses.
Implications:
- This case expands the known spectrum of Castleman disease presentations.
- Accurate diagnosis is crucial to avoid misclassification as malignancy.
- Awareness of hepatic Castleman disease can improve patient management and outcomes.