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Updated: Aug 15, 2026

Computed Tomography-guided Time-domain Diffuse Fluorescence Tomography in Small Animals for Localization of Cancer Biomarkers
Published on: July 17, 2012
Fluorine-18-fluorodeoxyglucose dual-head gamma camera coincidence imaging of recurrent colorectal carcinoma
H M Abdel-Dayem1, A I Radin, J Q Luo
1Department of Radiology, St. Vincent's Hospital and Medical Center of New York, and New York Medical College, Valhalla 10011, USA.
Abstract:
We report our experience with coincidence detection imaging of 18F-fluorodeoxyglucose (FDG) using a dual-head gamma camera. Scanning of the pelvis and abdomen of a patient with recurrent colorectal carcinoma showed recurrent disease in the pelvic floor and the base of the urinary bladder and metastatic disease in the retroperitoneal space of the pelvis. Although the tumor involving the bladder and pelvic floor was detected by CT and magnetic resonance imaging (MRI), metastatic spread to the retroperitoneal nodes on the left side was detected only by 18F-FDG imaging. Based on the ultrasound, CT, MRI and cystoscopy, a local recurrence of cancer was presumed in our patient. An exploratory laparotomy was performed to resect the tumor in its entirety. At the time of surgery, the retroperitoneal metastasis in the pelvis was confirmed. Had the findings of the coincidence detection imaging study been considered, the patient would have been spared the surgical procedure.
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