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Birth weight, gestational age and medications during pregnancy
1Department of Human Genetics and Teratology, National Institute of Hygiene-WHO Collaborating Centre for the Community Control of Hereditary Diseases, Budapest, Hungary.
Objective:
To determine the effect of medication on birth weight and gestational age in 29,004 healthy newborn infants born to mothers with or without treatment of drugs.
Method:
Birth weight and gestational age were evaluated in healthy control newborn infants in the population-based dataset of the Hungarian Case-Control Surveillance of Congenital Abnormalities (1980-1991) using multiple regression analysis.
Results:
Of 114 drugs used in more than 100 pregnant women, 19 had a positive or negative impact.
Conclusions:
Further studies should be carried out to identify the possible mechanisms of medication and/or the maternal disorder for which this medication was given.