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Published on: January 18, 2018
Successful treatment of a staphylococcal endocarditis vegetation with tissue plasminogen activator
R E Fleming1, S J Barenkamp, S B Jureidini
1Department of Pediatrics, St. Louis University School of Medicine, Missouri 63104, USA.
Abstract:
A 930 gm premature infant had Staphylococcal endocarditis with a tricuspid valvular vegetation that was unresponsive to antibiotics and not amenable to resection. Infusion of tissue plasminogen activator over a 3-day period completely lysed the vegetation. The infection cleared with continued antibiotics, and the infant recovered without sequelae.
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