Related Experiment Videos
Developmental signalling: a careful balancing act
1LGPD, Institut de Biologie du Développement de Marseille, CNRS/INSERM/Université de la Méditerranée/AP de Marseille, Campus de Luminy, Case 907, F-13288, Marseille, France. lemaire@lgpd.univ-mrs.fr
Current Biology : CB
|May 16, 1998
Abstract:
Embryos of arthropods and chordates are patterned along the dorso-ventral axis by a gradient of secreted morphogens of the Bmp4/Dpp family. This gradient now appears to be shaped by the opposing activities of Bmp-sequestering proteins, on the one hand, and Bmp-releasing metalloproteases, on the other.