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Related Experiment Videos

Intermittent claudication: symptom severity versus health values

S O de Vries1, W D Kuipers, M G Hunink

  • 1Department of Health Sciences, University of Groningen, The Netherlands.

Journal of Vascular Surgery
|April 18, 1998
PubMed
Summary

The verbal rating scale and EuroQol effectively measure health values in peripheral arterial occlusive disease patients, showing construct validity against symptom severity. Other instruments demonstrated less reliable associations with walking distance.

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Area of Science:

  • Health Economics
  • Quality of Life Research
  • Vascular Medicine

Background:

  • Intermittent claudication significantly impacts patients' health-related quality of life.
  • Accurate measurement of health values is crucial for assessing treatment effectiveness in peripheral arterial occlusive disease.

Purpose of the Study:

  • To evaluate the construct validity of five health value instruments in patients with intermittent claudication.
  • To examine the relationship between health values and symptom severity, specifically symptom-free walking distance.

Main Methods:

  • Ninety-two patients with intermittent claudication undergoing an exercise program were included.
  • Health values were assessed using the verbal rating scale, time trade-off, standard gamble, EuroQol, and Health Utilities Index (Mark III).

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  • Symptom severity was measured by symptom-free walking distance.

    • Main Results:

    • Average health values were lower in patients with shorter walking distances (< or = 150 m) across all instruments.
    • The verbal rating scale and EuroQol showed statistically significant differences in health values based on walking distance.
    • Individual patient data revealed heterogeneity, with moderate correlations between walking distance and health values for some instruments.

    Conclusions:

    • The verbal rating scale and EuroQol demonstrate evidence of validity for assessing health values in peripheral arterial occlusive disease patients.
    • These findings support the use of the verbal rating scale and EuroQol in clinical and research settings for this patient population.