Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Vestibular disease unmasked by hyperventilation

M L Bance1, M O'Driscoll, N Patel

  • 1Department of Otolaryngology, University of Toronto, Ontario, Canada.

The Laryngoscope
|April 18, 1998
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A qualitative study exploring the views of healthcare professionals regarding patients who have difficulty swallowing medicines.

International journal of clinical pharmacy·2026
Same author

Mechanical characterization of the human auricle for earable device design.

Journal of the mechanical behavior of biomedical materials·2025
Same author

The protected antimicrobial process in a University Teaching Hospital: a qualitative interview study exploring the knowledge, attitudes, and experiences of healthcare professionals.

International journal of clinical pharmacy·2022
Same author

Impact on patients of the coronovirus disease 2019 pandemic and postponement of cochlear implant surgery: a qualitative study.

The Journal of laryngology and otology·2021
Same author

Exploring factors having an impact on attitudes and motivations towards volunteering in the undergraduate nursing student population - A comparative study of the UK and Ghana.

Nurse education in practice·2021
Same author

Electrochemical impedance spectroscopy of human cochleas for modeling cochlear implant electrical stimulus spread.

APL materials·2020

Hyperventilation can reveal underlying vestibular disease, challenging the psychogenic view of dizziness. This study found hyperventilation effectively induced nystagmus in patients with vestibular deficits.

Area of Science:

  • Neurology
  • Otolaryngology
  • Vestibular Science

Background:

  • Dizziness from hyperventilation is often misattributed to psychogenic causes.
  • The impact of hyperventilation on individuals with existing vestibular disorders remains under-explored.

Purpose of the Study:

  • To investigate the diagnostic utility of hyperventilation in patients with unilateral vestibular deficits.
  • To compare the efficacy of hyperventilation versus head shake in eliciting nystagmus in vestibular disease models.

Main Methods:

  • Two patient groups with unilateral vestibular deficit were studied: postsurgery (acoustic neuroma resection) and presurgery (unoperated acoustic neuroma).
  • Participants underwent 90 seconds of hyperventilation.
  • Infrared videonystagmography was used to detect nystagmus.

Related Experiment Videos

  • A control group of healthy volunteers was also tested.

    • Main Results:

    • Hyperventilation induced nystagmus in 100% of postsurgery patients (n=32) and 82% of presurgery patients (n=28).
    • Hyperventilation proved more sensitive than head shake testing for detecting nystagmus in these patient groups.
    • The false-positive rate for hyperventilation in healthy volunteers was 3.5%, compared to 10% for head shake.

    Conclusions:

    • Hyperventilation is a valuable tool for unmasking subclinical or compensated vestibular deficits.
    • The findings suggest hyperventilation can serve as a sensitive diagnostic aid in evaluating dizziness, particularly when vestibular pathology is suspected.