Enchondromatosis with features of dysspondyloenchondromatosis and Maffucci syndrome
Related Experiment Video
Updated: Oct 30, 2026

Laser Capture Microdissection of Mouse Embryonic Cartilage and Bone for Gene Expression Analysis
Published on: December 18, 2019
N Haga1, K Nakamura, K Taniguchi
1Department of Pediatric Orthopedics, Shizuoka Children's Hospital, Shizuoka-city, Japan.
Abstract:
We report a girl with multiple enchondromatosis, unequal leg length, short stature, congenital scoliosis, lymphangioma, and cutaneous hemangiomata. The skeletal findings were consistent with the clinical and radiological features of dysspondyloenchondromatosis except that short stature was not apparent in the neonatal period. Dysspondyloenchondromatosis is a rare disorder, one of the several types of multiple enchondromatosis with spinal abnormalities. In previous reports of this condition the association of vascular lesions usually found in Maffucci syndrome has not been described.
Related Concept Videos
Cardiomyopathy III: Hypertrophic Cardiomyopathy
Bone Formation by Endochondral Ossification
Huntington Disease l: Introduction
Esophageal Achalasia
Bone Disorders
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Changes in the Appendicular Skeleton with Age
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...