Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Positive I-123-MIBG-scintigraphy in osteosarcoma

K von der Hardt1, H J Bair, T Kirchner

  • 1Department of Pediatrics, University of Erlangen-Nürnberg, Germany.

Nuklearmedizin. Nuclear Medicine
|April 21, 1998
PubMed
Summary

I-123-MIBG scintigraphy is standard for neuroendocrine tumors. This case shows positive uptake in pediatric osteosarcoma, highlighting that unusual results can occur with this imaging method.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Old carbon reservoirs were not important in the deglacial methane budget.

Science (New York, N.Y.)·2020
Same author

Integrity of dural closure after autologous platelet rich fibrin augmentation: an in vitro study.

Acta neurochirurgica·2020
Same author

Correlation of optic nerve and optic nerve sheath diameter with intracranial pressure in pigs.

PloS one·2020
Same author

Suitability of ultrasound-guided fine-needle aspiration biopsy for transcriptome sequencing of the canine prostate.

Scientific reports·2019
Same author

Meta-analysis of patient-reported outcomes after laparoscopic versus open inguinal hernia repair.

The British journal of surgery·2019
Same author

Fast track to the neocortex: A memory engram in the posterior parietal cortex.

Science (New York, N.Y.)·2018

Area of Science:

  • Nuclear Medicine
  • Oncology
  • Radiopharmaceuticals

Background:

  • I-123-MIBG scintigraphy is a well-established diagnostic tool.
  • It is primarily used for detecting neuroendocrine and neurocrest-derived tumors such as neuroblastoma and pheochromocytoma.

Observation:

  • A pediatric patient diagnosed with osteosarcoma was evaluated.
  • The patient underwent I-123-MIBG scintigraphy as part of their diagnostic workup.

Findings:

  • The I-123-MIBG scan revealed positive uptake in the osteosarcoma.
  • This finding is atypical as osteosarcoma is not typically considered a neuroendocrine or neurocrest-derived tumor.

Implications:

  • This case demonstrates that I-123-MIBG scintigraphy can yield unexpected positive results in non-traditional tumor types.

Related Experiment Videos

  • Clinicians should consider the possibility of unusual uptake patterns even with established imaging protocols.
  • Further investigation may be warranted to understand the biological basis for MIBG uptake in osteosarcoma.