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Gestational carrier pregnancy

S L Corson1, M Kelly, A M Braverman

  • 1Department of Obstetrics and Gynecology, Thomas Jefferson University School of Medicine and Pennsylvania Hospital, Philadelphia, USA.

Fertility and Sterility
|April 21, 1998
PubMed
Summary
This summary is machine-generated.

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Gestational carrier programs offer a successful solution for women with uterine or medical issues hindering pregnancy. Pregnancy rates were 56.3% in patients under 40, with no success in those over 40.

Area of Science:

  • Reproductive Medicine
  • Infertility Treatment
  • Assisted Reproductive Technology

Background:

  • Uterine or significant medical conditions can prevent successful gestation.
  • Gestational carrier programs provide an alternative for women unable to carry a pregnancy.
  • Evaluating the efficacy of these programs is crucial for patient care.

Purpose of the Study:

  • To assess the pregnancy and delivery rates of a gestational carrier program.
  • To compare outcomes between fresh and cryopreserved embryo transfer cycles.
  • To determine the success of gestational surrogacy for specific patient populations.

Main Methods:

  • Retrospective analysis of data from a private in vitro fertilization (IVF) program.
  • In vitro fertilization (IVF) of oocytes, followed by fresh or cryopreserved embryo transfer (ET) to gestational carriers.

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  • Patients included women with uterine or medical contraindications to carrying a pregnancy.

    • Main Results:

    • A pregnancy rate (PR) of 56.3% and a cycle live birth rate of 30.8% were achieved in 117 cycles for patients under 40 years of age.
    • No pregnancies were achieved in 27 cycles for nine patients over 40 years of age.
    • Outcomes were analyzed for both fresh and cryopreserved embryo transfers.

    Conclusions:

    • Gestational carrier programs provide a viable and effective option for achieving pregnancy in women with uterine or major medical challenges.
    • The program demonstrated satisfactory success rates for younger patients (<40 years).
    • Age appears to be a significant factor in the success of gestational carrier cycles.